Vitiligo and Lupus

Last Updated on 10th May 2022 by Caroline Haye

Diagram showing lupus symptoms


In considering possible links between vitiligo and other diseases, I didn’t want to leave out lupus. Because some of the medical literature suggests an association between the two conditions. And also for the altogether less scientific reason that Michael Jackson, who famously suffered from vitiligo for a large portion of his life, also had lupus.

What is lupus?

Before discussing whether or not there actually is any link between the two conditions it would, of course, be useful to know what lupus is.

Lupus is yet another autoimmune disease (one of around 80).  Autoimmune diseases occur when the body’s defence system produces antibodies that attack its own cells. This results in inflammation and disease. There are two main types of lupus. Discoid lupus erythematosus (DLE) – which only affects the skin. And systematic lupus erythematosus (SLE) – which can also affect the heart, lungs, kidneys, joints, and nervous system.   Up to 10% of people with discoid lupus (lupus limited to the skin) eventually develop the systemic form of lupus.

Lupus symptoms

SLE can cause various – often intermittent – symptoms in many different parts of the body. Most common are joint pains, skin rashes and extreme fatigue.  Its severity can range from very mild to extremely serious. This depends on which of the body’s organs are affected. And it is 8 – 9 times more common in women than in men.

Higher instances of other autoimmune disorders among those with vitiligo, as compared to the general population, have been very widely reported. In particular, autoimmune thyroid disease, pernicious anaemia and Addison’s disease and inflammatory bowel disease.  But, whereas autoimmune thyroid disease can quite often occur with systemic lupus erythematosus, instances of SLE existing alongside vitiligo are not especially common. And cases of vitiligo coexisting with discoid lupus erythematosus (DLE) are even more rare.

So, although vitiligo and lupus are both autoimmune diseases, the likelihood of having both lupus and vitiligo is relatively low.


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